Author: Dellepiane, G.
Paper Title Page
TUA02 Novel Irradiation Methods for Theranostic Radioisotope Production With Solid Targets at the Bern Medical Cyclotron 127
  • S. Braccini
    LHEP, Bern, Switzerland
  • C. Belver-Aguilar, T.S. Carzaniga, G. Dellepiane, P. Haeffner, P. Scampoli
    AEC, Bern, Switzerland
  • P. Scampoli
    Naples University Federico II, Napoli, Italy
  The production of medical radioisotopes for theranostics is essential for the development of personalized nuclear medicine. Among them, radiometals can be used to label proteins and peptides and their supply in quantity and quality for clinical applications represents a challenge. A research program is ongoing at the Bern medical cyclotron, where a solid target station with a pneumatic delivery system is in operation. To bombard isotope-enriched materials in form of compressed powders, a specific target coin was realized. To assess the activity at EoB, a system based on a CZT detector was developed. For an optimized production yield with the required radio nuclide purity, precise knowledge of the cross-sections and of the beam energy is crucial. Specific methods were developed to assess these quantities. To further enhance the capabilities of solid target stations at medical cyclotrons, a novel irradiation system based on an ultra-compact ~50 cm long beam line and a two-dimensional beam monitoring detector is under development to bombard targets down to few mg and few mm diameter. The first results on the production of Ga-68, Cu-64, Sc-43, Sc-44 and Sc-47 are presented.  
slides icon Slides TUA02 [37.771 MB]  
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About • paper received ※ 13 September 2019       paper accepted ※ 25 September 2019       issue date ※ 20 June 2020  
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