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TY - UNPB AU - Geets, J.-M. ED - Conradie, Lowry ED - De Villiers, John Garrett ED - Schaa, Volker RW TI - Radioisotopes Production in Accelerators & Cyclotrons Use J2 - Proc. of Cyclotrons2019, Cape Town, South Africa, 23-27 September 2019 CY - Cape Town, South Africa T2 - International Conference on Cyclotrons and their Applications T3 - 22 LA - english AB - The production of important medical radioisotopes mainly started with particle accelerators but, shortly after, some of them where totally forgotten due to the availability of nuclear reactors. SPECT isotopes where available in limited quantities with the first high energy positive ions machine; around 1985, the evolution of particle accelerator and the discovery of powerful negative ions cyclotron led to the creation of new companies. In the 1990’s, new compact and automated cyclotrons were instrumental in the development of PET radioisotopes (mainly 18F). Target design followed the beam power increase of such medium energy cyclotron as well as the need for new radioisotope with solid target. Recently, some companies are proposing very small cyclotrons for ’on the spot’ production at the point of use. There was revival of studies of Tc99m production with cyclotrons while some industrial players are looking at electron accelerators to produce the mother isotope Mo-99.The future seems bright for medical radioisotopes production with the replacement of old multi-particle or high energy accelerators by modern cyclotrons; there are new worldwide network of 30 & 70 MeV. PB - JACoW Publishing CP - Geneva, Switzerland ER -