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RIS citation export for TUB03: MRI-Guided-PT: Integrating an MRI in a Proton Therapy System

AU  - van der Kraaij, E.
AU  - Bertora, L.
AU  - Carrozzi, A.
AU  - Gantz, S.
AU  - Hoffmann, A.
AU  - Karsch, L.
AU  - Lühr, A.
AU  - Oborn, B.
AU  - Pawelke, J.
AU  - Schellhammer, S.
AU  - Serra, A.
AU  - Smeets, J.
ED  - Conradie, Lowry
ED  - De Villiers, John Garrett
ED  - Schaa, Volker RW
TI  - MRI-Guided-PT: Integrating an MRI in a Proton Therapy System
J2  - Proc. of Cyclotrons2019, Cape Town, South Africa, 23-27 September 2019
CY  - Cape Town, South Africa
T2  - International Conference on Cyclotrons and their Applications
T3  - 22
LA  - english
AB  - Integration of magnetic resonance imaging (MRI) in proton therapy (PT) has the potential to improve tumor-targeting precision. However, it is technically challenging to integrate an MRI scanner at the beam isocenter of a PT system due to space constraints and electromagnetic interactions between the two systems. We assessed the technical risks and challenges, and present a concept for the mechanical integration of a 0.5T MRI scanner (ASG MR-Open) into a PT gantry (IBA ProteusONE). Finite element simulations assess the perturbation of the gantry’s elements on the homogeneity of the scanner’s static magnetic field. MC simulations estimate the effect of the scanner’s magnetic field on the proton dose deposition. To test the technical feasibility, a first experimental setup was realized at the PT center in Dresden, combining a 0.22T open MRI scanner with a static proton beam line. Results show that the image quality is not degraded by proton beam irradiation if the acquisition is synchronized with beam line operation. The beam energy dependent proton beam deflection due to the scanner’s magnetic field is significant and needs to be corrected for in treatment planning and dose delivery.
PB  - JACoW Publishing
CP  - Geneva, Switzerland
SP  - 144
EP  - 147
KW  - proton
KW  - simulation
DA  - 2020/06
PY  - 2020
SN  - 978-3-95450-205-9
DO  - doi:10.18429/JACoW-Cyclotrons2019-TUB03
UR  - http://jacow.org/cyclotrons2019/papers/tub03.pdf
ER  -